Supply DeoxyArbutin CAS 53936-56-4
What is Deoxyarbutin?
Deoxyarbutin is a synthetic derivative of arbutin, designed to achieve more effective and safer skin brightening results. Compared to traditional α-arbutin and β-arbutin, it exhibits significantly higher stability—approximately 350 times that of β-arbutin and 38.5 times that of α-arbutin. As a competitive tyrosinase inhibitor, deoxyarbutin effectively regulates melanin production, helping to improve pigmentation, fade dark spots and uneven skin tone, resulting in a rapid and long-lasting brightening effect. It also possesses strong antioxidant capabilities, protecting against skin damage caused by free radicals. However, due to its high activity, the concentration of deoxyarbutin in formulations needs to be precisely controlled. Excessive dosage may cause mild skin irritation or sensitivity; therefore, it should be applied according to scientific formulation and proportioning techniques.
Why Choose YTBIO DeoxyArbutin?
Factory Strength & Qualifications
We are a 12+ years professional GMP manufacturer, certified with ISO, HACCP, HALAL, KOSHER, FDA. Full quality control system, stable production capacity, support OEM & ODM.
Premium Product Specifications
Purity ≥99% HPLC, white crystalline powder. Low heavy metal content, stable batch difference. Each batch comes with COA, third-party testing is supported.
Core Product Advantages
Powerful tyrosinase inhibition, better whitening effect than arbutin. Mild and low irritation, suitable for sensitive skin. Good water solubility, wide pH stability, compatible with most cosmetic raw materials, hard to discolor.
Application & Service
Mainly used in whitening, freckle fading, brightening skincare products. Free samples (freight collect). MOQ: 25kg bulk order. Provide professional cosmetic formulation technical support and complete after-sales service.
YTBIO: Providing High-Quality Deoxyarbutin and Services
Main Benefits of Deoxyarbutin
1. Inhibits Melanin Production
Deoxyarbutin is a highly effective competitive inhibitor of tyrosinase, blocking the conversion of tyrosine to dopa (DOPA), thus reducing melanin production at its source. By inhibiting the activity of this key enzyme, it effectively reduces pigmentation and significantly improves problem skin conditions such as melasma, freckles, and acne scars, resulting in a more even and radiant complexion.
2.Fades Dark Spots and Brightens Skin
With continued use, deoxyarbutin can significantly reduce melanin accumulation, fade existing dark spots, and brighten the overall skin tone, revealing a natural radiance and translucency.
3.Antioxidant Protection
Deoxyarbutin possesses excellent antioxidant capabilities, neutralizing free radicals, reducing skin damage caused by oxidative stress, helping to delay skin aging, and maintaining healthy and vibrant skin.
Features:
Highly Effective Whitening
Deoxyarbutin is a new generation of highly effective whitening active ingredient that significantly inhibits tyrosinase activity, blocking melanin production at its source. Studies show that its inhibitory capacity is approximately 38.5 times that of α-arbutin and 350 times that of β-arbutin, with a skin-brightening effect far superior to traditional ingredients such as hydroquinone and arbutin. After use, it can quickly improve dullness and pigmentation, resulting in a more even and radiant complexion, with long-lasting effects that maintain a bright appearance for several weeks even after discontinuation.
Safe and Gentle
As a competitive inhibitor of tyrosinase, deoxyarbutin reversibly regulates melanin synthesis by binding to the enzyme's active site without damaging melanocyte structure. Compared to traditional potent whitening ingredients like hydroquinone, it has lower cytotoxicity and irritation, is suitable for a wider range of skin types, and is safer.
Stability Requirements
Deoxyarbutin is sensitive to heat, light, and ultraviolet radiation in aqueous solutions and is prone to decomposition or discoloration. Therefore, stabilization technologies such as light protection, antioxidants, and pH control are required in the formulation design to ensure the product's activity and efficacy.
Deoxyarbutin: Applications
Cosmetics
Deoxyarbutin (D-Arbutin) is widely used in whitening and spot-fading skincare products, and is a new generation of highly effective brightening active ingredient.
Whitening and Spot Fading: By inhibiting tyrosinase activity, it blocks key steps in melanin production, effectively fading dark spots, improving uneven skin tone, and making the skin brighter and clearer. It is commonly used in high-end skincare products such as whitening serums, creams, lotions, and masks.
Antioxidant Skincare: It possesses excellent antioxidant capabilities, protecting against free radical damage and reducing oxidative stress-induced aging damage to the skin.
Pharmaceuticals and Functional Care
In dermatological research, deoxyarbutin is considered a potential adjuvant ingredient for treating pigmentation-related problems such as melasma, freckles, and post-inflammatory hyperpigmentation. Due to some controversy regarding its safety and stability, its clinical or pharmaceutical applications require strict control over concentration and formulation conditions.
Diverse Applications in Personal Care Products
Facial Care: Used in whitening serums, lotions, creams, etc., to improve uneven skin tone and fade dark spots.
Masks: Applied to sheet masks or clay masks for intensive brightening treatments.
Body Care: Added to body lotions, shower gels, etc., to help improve pigmentation on body parts.
Sunscreens: Works with sunscreen ingredients to prevent UV-induced melanin deposition and enhance skin tone protection.
FAQ
Q: Are you a formal manufacturer and what certifications do you have?
A: 12+ years GMP factory with full global certifications. OEM & ODM customization available.
Q: What specifications of DeoxyArbutin can you supply?
A: ≥99% HPLC white powder with low heavy metal. COA and third-party test supported.
Q: What are the prominent advantages of your DeoxyArbutin powder?
A: Strong whitening efficacy, mild formula, good water solubility, stable formula performance.
Q: What fields can this product be used in and how to store it properly?
A: Freckle and brightening skincare series. 24 months shelf life, store cool, dry and dark sealed environment.
Q: What’s your MOQ, production lead time?
A: 25kg standard MOQ,7-15 working days lead time.
Q: What after-sales support can you provide for buyers?
A: Cosmetic formulation technical guidance; return & exchange service for quality defects.
Email: sales@sxytbio.com
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