Pure Benfotiamine Vitamin B1 Derivative Powder
Benfotiamine: Product Introduction
Benfotiamine is the fat-soluble form of vitamin B1 (thiamine). After entering the body, it can be converted into physiologically active vitamin B1. Compared to water-soluble vitamin B1, benfotiamine has higher biological activity, with a bioavailability approximately 3.6 times greater. The increase in relative bioavailability is even more significant in muscle tissue (approximately 5 times greater) and brain nerves (approximately 25 times greater), allowing it to penetrate cell membranes more effectively, particularly facilitating absorption by the nervous system and brain.
Differences from Vitamin B1
Structural Characteristics: Benfotiamine is a fat-soluble derivative of vitamin B1, possessing an open thiazole ring. This structural feature allows it to form physiologically active vitamin B1 in vivo through ring-closure. Vitamin B1 itself does not possess such an open structure.
Absorption Mechanism: After oral administration, benfotiamine undergoes dephosphorylation in the gastrointestinal tract, forming a lipophilic molecule. This characteristic facilitates its diffusion into cell membranes, making it more readily absorbed than water-soluble vitamin B1. Vitamin B1, on the other hand, is water-soluble, and its absorption is relatively direct, but may be less efficient than that of benfotiamine.
Bioavailability: Due to its lipophilic nature, benfotiamine is absorbed more extensively in the intestines and target organs, resulting in significantly higher bioavailability than water-soluble vitamin B1. Specifically, the bioavailability of benfotiamine is 3.6 times that of water-soluble vitamin B1, up to 5 times in muscle tissue, and up to 25 times in the brain.
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ITEM |
STANDARD |
TEST RESULT |
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Assay |
≥98.0% |
99.3% |
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Physical & Chemical |
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Appearance |
White crystal or white crystalline powder |
Complies |
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Benzoic acid |
Not Detectable |
Complies |
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Thiamine |
≤0.1% |
0.05% |
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Sulfate |
≤0.011% |
0.003% |
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Chloride |
≤0.053% |
0.01% |
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Loss on Drying |
≤1.5% |
0.90% |
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Heavy Metal |
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Total Heavy Metals |
≤10ppm |
Complies |
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As |
≤3ppm |
Complies |
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Pb |
≤2ppm |
Complies |
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Conclusion |
Conform with specification |
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Storage |
Store in cool and dry places. Keep away from strong light and heat. |
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Packing |
By 25kgs/Drum, inner by double plastic bag |
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Shelf Life |
24 months under the above condition,and in it’s original package |
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Health Benefits
Benfotiamine improves nerve function by promoting the synthesis of neurotrophic factors in the brain, thereby relieving facial spasms. It is suitable for treating peripheral neuritis, megaloblastic anemia, and other diseases caused by vitamin B1 deficiency.
Benfotiamine is a fat-soluble form of vitamin B1 that can easily penetrate the myelin sheath of nerves, reaching the nerve itself and repairing damaged nerve function at its source. This fat-soluble vitamin B1 helps nerves regain energy and reduces the production of excessive lactic acid and other harmful metabolic byproducts, thus beginning to eliminate various complications caused by diabetes, not only in the leg nerves but also in damage to the eyes, kidneys, arteries, and even the brain.
Helps reduce the risk of chronic eye disease: There is evidence that the combination of thiamine and other nutrients may help reduce the risk of cataracts; benfotiamine has a higher absorption rate and faster effects.
Helps optimize symptoms of glucose metabolism disorders: Many patients with glucose metabolism disorders are deficient in thiamine. Glycation in the brain weakens the function of important proteins. Benzophosphatidylcholine helps prevent the harmful side effects of glucose metabolism and optimizes endothelial function.
Helps alleviate Alzheimer's disease: Oxidative stress and chronic inflammation in the brain are associated with metabolic diseases and cognitive impairment. Alzheimer's patients show reduced levels and activity of thiamine in their tissues and brains, which are associated with thiamine-dependent enzymes. Supplementation with benzfosamide may help optimize cognitive function.
Application Areas Overview
Benfotiamine can be used in powder form, exhibiting good flowability and stable purity. As a nutritional fortification ingredient, it is suitable for formulations in tablets, capsules, solid beverages, and nutritional powders.
This product can be precisely proportioned with compliant excipients, mixed, granulated, and then compressed into various forms, such as regular tablets, chewable tablets, and sustained-release tablets. It is the most common dosage form for dietary supplements and conditioning preparations.
Hard capsules can be directly filled with benfotiamine powder or granules; soft capsules are suitable for encapsulation with an oil-based matrix, effectively isolating moisture and light, significantly improving the storage stability of the ingredient, protecting it from external moisture and light, enhancing ingredient stability, and making it easy to swallow.
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Why Choose YTBIO's Benfotiamine?
With 12+ years of professional experience in functional nutritional raw material industry, YTBIO operates our own independent production factory, ensuring stable supply, strict quality control and reliable lead times from source to delivery.
We hold a complete set of authoritative international certifications, including cGMP, FSSC22000, BRC, HACCP, HALAL, KOSHER, ISO9001 and ISO22000, fully complying with global food safety and production standards.
We provide one-stop OEM & customized solutions for Benfotiamine. We can support standard specifications as well as tailor-made formulas, particle size, packaging and other personalized requirements to match your project demands.
If you are looking for high-quality Benfotiamine raw materials, please feel to contact our team for samples, COAs and the latest wholesale prices.
Email：sales@sxytbio.com
WhatsApp/phone：+86 17782577059
