Pharmaceutical-grade Nicotinamide Riboside and NAD+ precursor raw materials β trusted by global formulators and supplement brands.
Nicotinamide Riboside is a unique form of Vitamin B3 and a direct precursor to NAD+, the critical coenzyme driving cellular energy metabolism and longevity pathways.
π¬ Key Insight: NAD+ levels decline by up to 50% between the ages of 40 and 60. Supplementing with NR has been clinically shown to significantly raise NAD+ levels in blood, supporting mitochondrial function, DNA repair, and sirtuin activation β the core pillars of healthy aging.
NR efficiently converts to NAD+ inside cells, replenishing the mitochondrial energy currency and combating age-related fatigue. Clinical trials show measurable increases in cellular ATP production within weeks of supplementation.
Elevated NAD+ activates sirtuins (SIRT1βSIRT7), a family of longevity proteins that regulate gene expression, reduce inflammation, and enhance DNA damage repair β directly linked to slower biological aging.
Research published in Cell Metabolism highlights NR's role in protecting neurons, improving synaptic plasticity, and reducing neuroinflammation β offering promising applications in age-related cognitive decline and neurodegenerative conditions.
NR supplementation has demonstrated improvements in muscle stem cell regeneration and mitochondrial biogenesis in skeletal muscle, supporting healthy aging athletes and older adults seeking to maintain mobility and strength.
By boosting NAD+, NR supports healthy blood pressure regulation, lipid metabolism, and insulin sensitivity. Studies indicate reduced arterial stiffness and improved vascular function in adults supplementing with NR over 6β12 weeks.
NAD+ is essential for immune cell function. NR helps regulate inflammatory cytokine responses via CD38 pathways, offering potential benefits for chronic low-grade inflammation β a hallmark of accelerated aging.
Over a decade of expertise in producing pharmaceutical-grade NAD+ precursors and nutritional supplement raw materials.
The global Nicotinamide Riboside market is experiencing explosive growth, driven by aging populations, longevity research breakthroughs, and expanding consumer health awareness.
The global NR supplement market was valued at over USD 300 million in 2023 and is projected to exceed USD 900 million by 2030, growing at a CAGR of approximately 17β19%. North America leads consumption, while Asia-Pacific is the fastest-growing region, driven by China, Japan, and South Korea's aging demographics and rising health supplement adoption.
China has emerged as the world's primary NR raw material manufacturer, accounting for over 70% of global API-grade NR production. Advanced biosynthesis and enzymatic conversion technologies have dramatically reduced production costs, enabling mass-market supplement formulations while maintaining pharmaceutical-grade purity standards above 98%.
Over 50 registered clinical trials are currently investigating NR's applications in Alzheimer's disease, Parkinson's disease, metabolic syndrome, cardiovascular aging, and cancer supportive care. Major pharmaceutical companies and biotech firms including Elysium Health, ChromaDex, and Jinko Pharmaceutical are investing heavily in NR-based therapeutic pipelines, signaling the ingredient's transition from supplement to clinical nutraceutical.
Beyond traditional capsules and powders, the industry is witnessing rapid innovation in NR delivery formats: liposomal NR for enhanced bioavailability, sublingual tablets for rapid absorption, NR-NMN combination stacks for synergistic NAD+ elevation, and topical NR serums targeting skin aging. Functional food and beverage applications are also emerging, with NR-fortified drinks entering the premium wellness market.
From precision longevity clinics to mass-market supplements β Nicotinamide Riboside is reshaping how industries approach healthy aging.
NR is the cornerstone ingredient in high-end anti-aging supplement stacks, often combined with Resveratrol, NMN, Quercetin, and CoQ10. Brands targeting the 40+ demographic position NR-based products as daily cellular health investments commanding premium price points of $60β$150 per bottle.
NR is being investigated as an adjunct therapy in metabolic disease management, chemotherapy-induced peripheral neuropathy, and post-COVID fatigue syndrome. Functional medicine clinics increasingly recommend NR protocols as part of personalized longevity programs alongside comprehensive biomarker testing.
Elite sports nutrition brands are incorporating NR for its mitochondrial biogenesis benefits, helping athletes recover faster, sustain higher training loads, and maintain peak performance as they age. NR is particularly popular in masters athletics and endurance sports communities.
The beauty industry is leveraging NR's NAD+ boosting properties in premium skincare. Topical NR formulations target mitochondrial skin aging, promoting collagen synthesis, reducing UV-induced DNA damage, and improving skin barrier function β a rapidly growing segment within the $500B global beauty market.
NR is entering the functional food space through fortified beverages, longevity shots, and nootropic drinks. Japanese and Korean markets lead in NR-infused wellness drink adoption, with products positioned as daily cellular energy and brain health beverages targeting urban professionals aged 30β55.
An emerging frontier: NR supplementation for companion animals. Veterinary research indicates similar NAD+ decline patterns in aging dogs and cats, with early studies showing improved mobility, cognitive function, and vitality in senior pets β opening a new commercial channel for NR ingredient suppliers.
YTBIO offers complete NR and NAD+ ingredient solutions from raw material supply to finished product OEM/ODM manufacturing.

Our NR and NAD+ raw material range β including Nicotinamide Riboside Chloride, Ξ²-NMN, NAD+, and NADH β are primarily used in longevity supplements, pharmaceutical applications, and functional health products. These ingredients replenish critical cellular coenzymes required for energy metabolism, DNA repair, and healthy aging.
YTBIO has over ten years of experience in NAD+ precursor raw materials and supports OEM/ODM services. Through continuous innovation and commitment to quality, we provide reliable healthy aging ingredient solutions to global customers.
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Our NR capsule range includes hard capsules, soft capsules, and pellet capsules featuring Nicotinamide Riboside, NMN, NAD+, and combination longevity formulas. All ingredients, packaging, and labels can be fully customized to your brand specifications.
We specialize in custom NR formulations including NR+Resveratrol, NR+NMN synergy blends, and NR+CoQ10 mitochondrial support stacks. GMP-compliant production ensures consistent purity and potency in every batch.
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Our NR tablet manufacturing utilizes advanced boiling granulation, direct powder compression, and semi-film coating technologies to deliver stable, bioavailable NR tablets. Customization options include NR dosage, tablet shape, packaging, and branding.
All production materials meet national and international standards, with comprehensive QA/QC inspection at every stage β from raw NR ingredient testing to finished tablet release testing β ensuring product safety, stability, and efficacy.
See MoreA decade of innovation in NR, NAD+ precursors, and premium nutritional supplement raw materials.

Since its establishment in 2014, Shaanxi Yuantai Biological Technology Co., Ltd. has always focused on the research, development, production and sales of herbal extracts, nutritional supplements, organic products and OEM/ODM services. With high standards of product quality and a professional team as the core, the company provides customers with high-quality health product solutions. It always adheres to the concept of sustainability, balance and health to ensure that the products meet market demand and consumer expectations.
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All YTBIO products are produced by ourselves, covering an area of 10,000+ square meters, with advanced extraction equipment and mature extraction technology. Separate production areas for capsules, granules, tablets, solid beverages, etc.

Production facilities and equipment meet national standards. The production process is strictly carried out in accordance with GMP requirements. We constantly update QA/QC standards to enhance core competitiveness in quality control and R&D levels.

Certificates obtained include cGMP, FSSC22000, BRC, HACCP, ISO9001, ISO22000, HALAL, KOSHER, FDA, organic and other international quality certifications.
Looking for pharmaceutical-grade Nicotinamide Riboside, NMN, or NAD+ raw materials? Get competitive pricing and customized solutions from our expert team.
Provide customers with quality NR and longevity ingredients. For product information and quotes, contact us!
99%
80 Mesh, 200 Mesh
30g, 50g
180 pcs/bag
60 PCS/Bottle
120 PCS/Bottle
120 Capsules/Bottle
60 PCS/Bottle
YTBIO covers an area of 10,000+γ‘ and has passed cGMP, FSSC22000, BRC, ISO9001, ISO22000, KOSHER, HALAL, FDA, and organic certifications. The production process is strictly carried out in accordance with scientific production process to ensure the safety, stability and effectiveness of the products. We have established a modern quality management system including inspection of raw materials, intermediates, and finished products, as well as full monitoring of the production process.
Our NR and NAD+ ingredients are manufactured under the world's most stringent quality and safety standards.





















Explore our full range of NAD+ precursors and healthy aging raw materials β all manufactured to pharmaceutical-grade standards.



Whether you need bulk NR raw material, custom NR capsule OEM, or a complete longevity supplement formulation β our expert team is ready to support your business.