Manufacturer Supply S-Acetyl-L-glutathione 98%
S-Acetyl-L-Glutathione: Introduction
S-Acetyl-L-Glutathione (SAG) is a stable form of glutathione. Through acetylation modification, the acetyl group is combined with the active sulfhydryl group of glutathione, which not only enhances the chemical stability of the molecule but also significantly improves its bioavailability. Compared to traditional reduced glutathione, SAG retains its original antioxidant and detoxification functions while exhibiting significant advantages in absorption efficiency, cell penetration, and practical application performance.

YTBIO provides you with S-acetyl-L-glutathione raw materials with 98%+ purity and supports the development and supply of related finished products, offering you a one-stop solution.
CERTIFICATE OF ANALYSIS
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ITEM |
STANDARD |
TEST RESULT |
|
|
S-Acetyl-L-Glutathione (By HPLC) |
98.0%~101.0% |
98.31% |
|
|
Physical & Chemical |
|||
|
Appearance |
Almost White to White Crystalline Powder |
Complies |
|
|
Solubility |
Soluble in water |
Complies |
|
|
Identification |
Positive |
Complies |
|
|
Appearance of solution |
Clear And Colorless |
Complies |
|
|
Loss On Drying |
≤0.5% |
0.43% |
|
|
Heavy Metal |
|||
|
Total Heavy Metals |
≤10ppm |
Complies |
|
|
As |
≤2ppm |
Complies |
|
|
Pb |
≤2ppm |
Complies |
|
|
Microbiological Test |
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|
Total Plate Count |
≤1,000cfu/g |
<100cfu/g |
|
|
Mold and Yeast |
≤100cfu/g |
<10cfu/g |
|
|
E.Coli |
≤10cfu/g |
<0.3cfu/g |
|
|
Salmonella |
Negative |
Negative |
|
|
Staphylococcus |
Negative |
Negative |
|
|
Conclusion |
Conform with specification |
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|
Storage |
Store in cool and dry places. Keep away from strong light and heat. |
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|
Packing |
By 25kgs/Drum, inner by double plastic bag |
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|
Shelf Life |
24 months under the above condition,and in it’s original package |
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S-Acetyl-L-Glutathione: Advantages and Characteristics
Stability and Solubility
Acetylation modification protects glutathione molecules from degradation by gastrointestinal digestive enzymes, allowing them to reach the absorption site intact. At the same time, S-acetyl-L-glutathione possesses excellent solubility, facilitating the development and application of various dosage forms.
Bioavailability
Its lipophilic structure allows SAG to efficiently penetrate cell membranes and rapidly convert into active glutathione once inside the cell. Studies show that its oral absorption efficiency is 3-5 times higher than that of ordinary glutathione, more effectively increasing intracellular glutathione levels and improving related indicators.
Gentle and Non-Irritating
S-acetyl-L-glutathione has a milder odor and a more palatable taste, making it suitable for use in food and oral beauty products. While enhancing intracellular antioxidant capacity, it does not increase the body's metabolic burden.
S-Acetyl-L-Glutathione: Main Efficacy and Applications
1. Antioxidant and Anti-aging
As a highly effective free radical scavenger, S-acetyl-L-glutathione protects cells from oxidative damage, slows collagen degradation, and maintains mitochondrial function, thereby helping to delay the aging process.
2. Skin Whitening
S-acetyl-L-glutathione reduces melanin production at its source by inhibiting tyrosinase activity, improving uneven skin tone and dullness. Its anti-inflammatory and repairing properties also help strengthen the skin barrier.

3. Liver Protection
SAG is an important cofactor for liver detoxification, neutralizing toxic metabolites, reducing damage to liver cells from alcohol, drugs, and environmental toxins, and supporting healthy liver function.
4. Immune Regulation
SAG helps optimize the immune response and enhance the body's resistance by increasing intracellular glutathione reserves.
5. Healthy Blood Circulation
SAG protects hemoglobin from oxidation, prevents the formation of methemoglobin, maintains the normal oxygen-carrying function of red blood cells, and supports overall healthy blood circulation.
Acetylglutathione, with its high efficiency, stability, and easy absorption, has been widely used in high-end dietary supplements, oral beauty products, functional foods, and medical nutrition support.
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Application Areas |
Application Forms |
Core Functions |
|
Functional Foods |
Dietary supplements, sports nutrition preparations, etc.; |
As an antioxidant, it eliminates excess reactive oxygen species after exercise, reducing oxidative damage to muscles; it also helps improve metabolic function; |
|
Cosmetics |
Efficacy serums, repair creams, whitening masks, etc.; |
It achieves skin whitening by inhibiting tyrosinase activity sites and accelerating melanosome degradation; it penetrates the dermis to eliminate free radicals, protect collagen fibers, and delay photoaging; |
|
Pharmaceutical Support |
Oral liver-protecting preparations, antioxidant adjuvant therapy drugs, etc. |
It enhances detoxification function by increasing glutathione levels in liver cells; and it serves as an adjunct intervention for oxidative stress-related diseases. |

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