Factory Supply 99% L-Citrulline Powder CAS 372-75-8
L-Citrulline: Product Introduction
L-citrulline is an α-amino acid widely found naturally in cucurbitaceous plants such as watermelon and winter melon. It is a non-protein amino acid. In the human body, citrulline can be synthesized from ornithine via the urea cycle, or it can be synthesized in the intestines from glutamine. Approximately 13% of glutamine ingested in the intestines is converted into citrulline. Citrulline plays a crucial role in the body's metabolism. It is not only an important intermediate in the urea cycle, responsible for converting toxic ammonia produced by protein metabolism into non-toxic urea for excretion, but it also participates in regulating muscle protein synthesis, immune responses, and antioxidant defense. As a functional amino acid, citrulline has been widely used in the pharmaceutical, health product, and food industries.

Health Benefits
Urea Cycle and Detoxification
L-citrulline participates in the body's urea cycle. Daily protein metabolism produces excess ammonia, which citrulline converts into urea and excretes. This is crucial for maintaining the body's acid-base balance and eliminating toxic metabolic waste. Especially during exercise, muscle ammonia production increases; L-citrulline helps remove ammonia through the urea cycle, thus reducing fatigue.
Cardiovascular Protection
Supplementing with L-citrulline can increase arginine levels in the blood, promote nitric oxide production, help improve vascular endothelial function, and lower blood pressure.
Muscle Regulation
L-citrulline not only aids in muscle repair and regeneration but also promotes muscle protein synthesis, playing a positive role in maintaining muscle mass and improving athletic performance.
Immune Regulation and Anti-inflammatory Effects
L-citrulline also plays a role in the immune system. It can promote the proliferation and function of immune cells, enhancing immunity. In addition, L-citrulline possesses certain anti-inflammatory and antioxidant properties, reducing the release of inflammatory cytokines and protecting cells from oxidative stress damage.
Anti-aging effects
Recent scientific research has found that L-citrulline levels decline significantly with age and are associated with age-related metabolic disorders. L-citrulline supplementation has been shown to reduce cellular senescence, prevent DNA damage, regulate cellular metabolism, and alleviate chronic inflammation.
Application Areas Overview
Sports Nutrition
Enhancing Athletic Performance: Citrulline supplementation can improve exercise endurance, enhance muscle strength, and reduce post-exercise muscle soreness and fatigue. It is widely used in sports nutrition supplements.
Beauty & Skincare
Antioxidant and Anti-aging: Citrulline has antioxidant properties, scavenging free radicals, protecting cells from oxidative damage, and delaying skin aging. It is commonly used in high-end skincare products and masks, helping to reduce wrinkles and improve skin texture.
Food & Beverage
Functional Food Additive: As a natural amino acid, citrulline can be added to beverages, solid beverages, chewable tablets, and other foods to provide health benefits such as enhancing immunity and improving digestive function.
Pharmaceuticals & Healthcare
Cardiovascular Health Ingredient: By generating nitric oxide, it helps dilate blood vessels and reduce peripheral resistance, making it suitable for improving cardiovascular microcirculation in middle-aged and elderly individuals. It is an important ingredient in antihypertensive and heart-protective health products.
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Why Choose YTBIO L-Citrulline?
As a professional manufacturer with 12+ years of deep engagement in natural plant extracts and nutritional supplement raw materials, YTBIO boasts self-owned production bases and stable supply capacity to guarantee consistent quality and fast delivery.
Our products and production lines have obtained authoritative global certifications including cGMP, FSSC22000, BRC, HACCP, HALAL, KOSHER, ISO9001 and ISO22000, fully complying with international quality and safety standards for food applications.
Beyond standard specifications, we provide full-process one-stop OEM & customization services. We can tailor-make specifications, formulations and packaging strictly according to your project requirements.
If you are looking for high-quality L-Citrulline , feel free to reach out anytime for samples, COA document and the latest wholesale price.
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