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CAS 51446-62-9 Phosphatidylserine Powder
What is phosphatidylserine?
Phosphatidylserine (PS) is a naturally occurring bioactive substance with essential physiological functions, serving as a key component of cell membranes. This unique phospholipid molecule is primarily extracted from soybean oil residues and consists of three structural parts: a hydrophobic tail formed by two long-chain fatty acids, a glycerol backbone as a connecting bridge, and a negatively charged hydrophilic head group composed of serine and a phosphate group. This amphipathic nature (containing both hydrophilic and hydrophobic regions) allows PS to seamlessly integrate into the bilayer structure of cell membranes, where it is particularly abundant in brain nerve cells.
As a crucial functional molecule in the nervous system, PS exhibits multiple biological effects. Due to its strong lipophilic properties, it can rapidly cross the blood-brain barrier and directly act on the central nervous system. In the brain, PS optimizes neuronal membrane fluidity, regulates neurotransmitter release and nerve impulse transmission, and improves cerebral microcirculation by relaxing vascular smooth muscles, thereby enhancing blood supply to brain tissues. These combined actions contribute to cognitive enhancement, with the most notable effect being improved memory function. Notably, naturally occurring PS is not a single chemical entity but rather a group of structurally similar compounds with varying long-chain fatty acid compositions. This structural diversity may be closely linked to its broad functional adaptability.
Core Benefits of Phosphatidylserine (PS)
1. Enhancing Cognitive Function & Restoring Brain Vitality
● Promotes dopamine release and glutamate-mediated neurotransmission.
● Significantly improves cognitive functions such as learning and memory.
● Backed by over 3,000 international studies confirming its effectiveness in enhancing brain function.
2. Stress Management & Mood Regulation
● Reduces stress hormone levels in individuals under high work pressure.
● Alleviates mental fatigue and enhances concentration.
● Modulates neurotransmitters that influence mood.
● Helps relieve negative emotions such as depression and anxiety.
3. Athletic Performance & Recovery
● Regulates adrenocorticotropic hormone (ACTH) and cortisol secretion.
● Increases the testosterone-to-cortisol ratio.
● Reduces post-exercise muscle amino acid loss.
● Speeds up physical recovery and alleviates muscle soreness.
● Improves athletes' psychological state and competition mindset.
4. Memory Enhancement in Children
● Serves as an essential nutrient for brain development.
● Helps children build clearer and stronger memory capacity.
● Continuous supplementation significantly boosts brain function.
Application direction
Phosphatidylserine (PS), as a crucial functional ingredient, has gained widespread recognition from international regulatory authorities. In 2006, PS received approvals from both South Korean and U.S. regulatory agencies. In May of that year, the Korea Food and Drug Administration (KFDA) officially permitted PS-containing products to carry health claims such as "improving mood, enhancing memory, and preventing Alzheimer's disease." Subsequently, in October, the U.S. Food and Drug Administration (FDA) classified PS as a "Generally Recognized as Safe" (GRAS) substance, approving its use as a nutritional fortifier in various everyday foods, including yogurt, milk powder, bread, and instant drink powders. These regulatory certifications not only confirm the safety of PS but also officially acknowledge its significant benefits in cognitive function and emotional well-being, providing legal support for its application in the functional food industry.
