CAS 25104-18-1 Polylysine Powder
What is Polylysine?
Polylysine is a natural polypeptide biopreservative that has been successfully used in food preservation since the 1980s. Its unique combination of antimicrobial properties and nutritional value makes it an ideal food preservative: it is broken down in the human body and converted into lysine, one of the eight essential amino acids and an internationally recognized safe food fortifier. This metabolizable property gives polylysine a significant safety advantage over traditional chemical preservatives, achieving the dual benefits of preservation and nutritional enhancement.
What are the benefits
Immune Enhancement and Antioxidant Effects
Polylysine is rich in bioactive amino acid residues such as glutamyl-arginyl dipeptide. By activating immune cell function, it significantly enhances the body's defenses and effectively resists pathogen invasion. Furthermore, its potent antioxidant properties precisely neutralize free radicals, blocking oxidative chain reactions, protecting cell structural integrity, and slowing the aging process.
Blood Pressure Regulation Mechanism
Polylysine regulates blood pressure through multiple pathways: selectively inhibiting angiotensin I-converting enzyme (ACE) activity, reducing the production of vasoconstrictor substances; simultaneously promoting the synthesis and release of nitric oxide (NO) by endothelial cells, repairing endothelial function. These dual actions synergistically achieve vasodilation and lower blood pressure.
Comprehensive Protection of the Cardiovascular System
Polylysine exhibits multiple benefits in the prevention and treatment of cardiovascular disease: regulating lipoprotein metabolism, inhibiting the oxidative deposition of low-density lipoproteins; improving endothelium-dependent vasodilation; and blocking key pathways in the formation of atherosclerotic plaques. These actions collectively form a protective network for cardiovascular health, significantly reducing the risk of cardiovascular and cerebrovascular diseases.
Applications
1. Applications in Food
Currently, polylysine is widely used in foods and beverages such as cakes, pastries, fast food, butter, salad dressing, beverages, alcohol, meat products, and canned goods. The national standard dosage for different food types can be found in the table below. Food Category Number Food Name Usage Amount
07.0 Baked Goods 0.15g/kg
08.03 Cooked Meat Products 0.25g/kg
14.02 Fruit and Vegetable Juices 0.20g/l
In addition, polylysine can be used as an effective cleaning and disinfectant for food processing machinery and containers.
2. Applications in Cosmetics and Daily Chemicals
Cosmetics are highly susceptible to microbial contamination and spoilage during production, storage, and use. Deterioration and mold caused by microbial contamination can pose a serious threat to human skin. Polylysine has broad-spectrum antimicrobial properties, effectively inhibiting the growth of various microorganisms and ensuring product quality. Polylysine is a polymer of amino acids and a nutritional preservative, making it more environmentally friendly, safe, and effective. ε-polylysine is also widely used in daily chemical products such as toothpaste, mouthwash, soap, hand sanitizer, wet wipes, kitchen cleaner, sanitary napkins, and baby diapers.
3. Applications in Medicine
Polylysine is rich in cations, generating strong electrostatic interactions with anionic substances and possessing excellent penetration into biological membranes. This property allows polylysine to be used as a carrier for certain drugs, leading to its widespread use in pharmaceuticals. Polylysine polymerized with amethoxazole can enhance drug efficacy. Studies investigating the extent of damage to cell membranes modified with polylysine of varying molecular weights by electric pulses have shown that adsorption of high-molecular-weight polylysine reduces the critical voltage for cell membrane damage.
