Bulk Wholesale L-Hydroxyproline Powder CAS 51-35-4
L-Hydroxyproline: Product Introduction
L-Hydroxyproline is an imino acid, a non-essential amino acid isolated from another amino acid called proline. It is produced through the interaction of proline with ascorbic acid and vitamin C. It is a major component of collagen tissue and a unique amino acid found in collagen, accounting for approximately 13% of the total amino acids in collagen. Collagen is the most abundant protein in the body, accounting for about one-third of the total protein in the human body. It plays a crucial role in human tissues such as skin, bones, and connective tissue by enhancing the stability of collagen structure, and is widely used in the pharmaceutical, skincare, and food industries.
Our bodies can synthesize L-hydroxyproline, but the efficiency of this synthesis declines with age. Therefore, proactive supplementation is crucial.
Natural food sources of L-hydroxyproline:
Animal-derived: Pig's trotters, beef tendons, fish skin, chicken feet, bone broth, etc. The collagen in these foods, after digestion, releases various amino acids, including L-hydroxyproline.
How to efficiently replenish?
Choose our YTBIO L-hydroxyproline.
We use a microbial fermentation process, replacing traditional chemical synthesis or animal protein hydrolysis. It is free of strong acids and alkalis, carries no animal-derived risks, has no solvent residue, meets food-grade standards, and has a purity of ≥98%, making it suitable for the food industry.
| Item | Specification |
| Melting Point | 274-275℃ |
| Solubility | Water: 50 mg/mL |
| Specific Rotation | -74° ~ -77° (c=5, H₂O) |
| Loss on Drying | <0.2% |
| Chloride (Cl) | < 200 PPM |
| Sulfate (SO₄) | < 200 PPM |
| Ammonium (NH₄) | < 200 PPM |
| Iron (Fe) | < 10 PPM |
| Refractive Index | -75.5° (C=4, H₂O) |
Health Benefits
Mechanism of Action of Hydroxyproline
●Large molecular weight allows for transdermal absorption.
●L-Hydroxyproline is a crucial factor in the formation of collagen and elastin: Collagen and elastin are widely present in the dermis of the skin (accounting for approximately 70%). Collagen peptides are mainly composed of amino acids, with glycine, proline, alanine, and hydroxyproline accounting for over 60%, and L-hydroxyproline accounting for approximately 10%. L-hydroxyproline is an important amino acid that stabilizes the triple helix structure of collagen peptides.
The "Guardian of Youth" for Skin
L-hydroxyproline is a unique amino acid in skin collagen. Collagen content is generally represented by a ratio of 7.46 times that of hydroxyproline. A decrease in hydroxyproline content in the dermis can be used as an indicator of skin aging. L-hydroxyproline is a major component of collagen fibers in the dermis. Sufficient L-hydroxyproline ensures a stable collagen structure, acting like a strong "elastic net" to support the skin, thus maintaining its plumpness, hydration, and elasticity, and delaying the appearance of wrinkles and sagging.
The "Lubricant" and "Structure" of Joints and Bones
Cartilage, tendons, and ligaments are rich in collagen. L-hydroxyproline is a major component of collagen tissue and a unique amino acid found in collagen. Effective supplementation of hydroxyproline can help maintain the strength and flexibility of these connective tissues, reducing joint wear, improving flexibility, and providing solid support for bones.
The "Accelerating Engine" of Wound Healing
After tissue injury, hydroxyproline can stimulate fibroblast proliferation and matrix synthesis, thereby accelerating the wound healing process. L-hydroxyproline, as a raw material for synthesis, is crucial for promoting wound healing and tissue regeneration.
Neuroregulatory Role
L-hydroxyproline is a major component of collagen, the most abundant protein in nerve tissue. Hydroxyproline is a non-protein amino acid that plays a vital role in neural development. It participates in the growth, differentiation, and maturation of neurons and glial cells. It helps maintain the structure and function of the extracellular matrix, providing support and protection for neurons. It also participates in the synthesis and release of neurotransmitters, such as glutamate and gamma-aminobutyric acid (GABA).
Application Areas Overview
Nutritional Fortifier
L-hydroxyproline is an important component of collagen. Adding it to food as a nutritional fortifier helps supplement the body's required nutrients, promotes collagen synthesis, and plays a vital role in maintaining the health of skin, bones, joints, and other tissues. For example, L-hydroxyproline is often added to some sports nutrition foods and nutritional supplements for the elderly to help athletes repair muscle tissue and to help the elderly maintain bone and joint health.
Flavor Enhancer
In the meat processing and baking industries, it can undergo Maillard reactions with other amino acids and sugars to produce unique flavors and colors, enhancing the aroma and taste of food. L-hydroxyproline utilizes this property to improve the flavor of products. For example, in grilled meat products, it gives the meat a richer aroma and an appealing color.
Wound Healing Promoter
As a key raw material for collagen synthesis, L-hydroxyproline promotes fibroblast formation and collagen deposition, which helps with wound healing and tissue repair. In the treatment of burns and trauma, medications or dressings containing L-hydroxyproline can accelerate the wound healing process and reduce scar formation.
Ingredients in health supplements
L-hydroxyproline is found in some collagen oral liquids and joint health capsules. It is used to prevent and improve diseases related to collagen loss, such as osteoporosis, arthritis, and skin aging.
Skin care
L-hydroxyproline has strong hydrophilic properties, allowing it to penetrate the stratum corneum of the skin. It promotes skin cell metabolism, enhances the skin's water retention capacity, and makes the skin softer, smoother, and more elastic. It is often added to face creams, lotions, serums, and other skincare products to improve dry and rough skin and delay skin aging.
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Why Choose YTBIO's L-Hydroxyproline?
With 12+ years of professional experience in functional nutritional raw material industry, YTBIO operates our own independent production factory, ensuring stable supply, strict quality control and reliable lead times from source to delivery.
We hold a complete set of authoritative international certifications, including cGMP, FSSC22000, BRC, HACCP, HALAL, KOSHER, ISO9001 and ISO22000, fully complying with global food safety and production standards.
We provide one-stop OEM & customized solutions for L-Hydroxyproline. We can support standard specifications as well as tailor-made formulas, particle size, packaging and other personalized requirements to match your project demands.
If you are looking for high-quality L-Hydroxyproline raw materials, please feel to contact our team for samples, COAs and the latest wholesale prices.
Email：sales@sxytbio.com
WhatsApp/phone：+86 17782577059
