98% HPR Hydroxypinacolone Retinoate CAS 893412-73-2
Do you know HPR Hydroxypinacolone Retinoate?
HPR Hydroxypinacolone Retinoate is a novel retinoid ingredient that combines the advantages of both retinol and retinol esters. It acts directly on the skin without requiring metabolic changes or biodegradation into other forms. It regulates epidermal and stratum corneum metabolism, offers anti-aging benefits, reduces sebum secretion, and lightens epidermal pigmentation, helping to prevent skin aging, acne, and whiten and lighten dark spots. While maintaining the powerful effects of retinol, it significantly reduces its irritation, making it widely used in skincare products.
A type of vitamin A, HPR is a new generation of retinoic acid esters, formed by the esterification of retinoic acid and the small molecule pinacol. Unlike other retinoic acid derivatives, HPR retains the functional groups of retinoic acid, eliminating the need for conversion to retinoic acid. It can act directly on retinoic acid receptors, exerting its anti-aging effects similar to those of all-trans retinoic acid.
Compared to traditional retinol, HPR Hydroxypinacolone Retinoate not only binds directly to retinol receptors, but also works without undergoing any conversion process. Its immediate effects, small molecular weight, and improved transdermal absorption make it gentler and more stable.
Advantages of HPR Hydroxypinacolone Retinoate
Retinol esters, retinol, and retinal all must be converted to retinoic acid to function. This conversion process can be limited by enzyme activity, local delivery, and stability, often weakening or even losing activity during the conversion process. Each conversion process results in losses, requiring a larger dosage of retinols to achieve the same effects as retinoic acid. Furthermore, the conversion process can easily cause skin irritation and side effects such as burning, redness, itching, and red streaks. Unlike retinol, retinal, and retinoic acid esters, HPR works without conversion, thus minimizing losses during the conversion process and resulting in greater activity. It is also more biologically active than retinol and other non-VA acid derivatives.
Mechanism of action: The binding of HPR to retinoic acid receptor RAR can enhance the expression of related genes, effectively transform the opening and closing functions of key cells, promote cell proliferation, biosynthesis of extracellular proteins and polysaccharides, and improve cell metabolism, thereby achieving the effect of anti-wrinkle and lightening.
YTBIO: Providing High-Quality HPR Hydroxypinacolone Retinoate and Services
High-quality nutritional supplements are crucial to your health journey. YTBIO specializes in providing high-quality HPR Hydroxypinacolone Retinoate.
Why choose YTBIO? We hold the following certifications:
- cGMP, ISO9001, and ISO22000 certifications ensure rigorous quality control throughout the entire process;
- BRC and HACCP system certifications ensure product safety and reliability;
- EU and NOP organic, kosher, and halal certifications meet various global standards and dietary requirements.
We specialize in the research, development, and production of natural plant extracts, cosmetic active ingredients, and health foods. We primarily produce plant extracts, health food ingredients, and a variety of end-use products, including capsules, softgels, granular capsules, gummies, tablets, and solid beverages. Our production facilities and equipment meet national standards, and our production processes strictly adhere to GMP requirements. If you have any questions, please feel free to contact us at sales@sxytbio.com
Skincare Benefits of HPR Hydroxypinacolone Retinoate
Anti-aging and Anti-wrinkle
Promotes the synthesis of hyaluronic acid and collagen in the dermis, preventing excessive collagen degradation.
Brightens skin tone
Promotes cell differentiation and renewal, improving skin roughness; inhibits tyrosinase activity, whitens skin, and reduces age spots and pigmentation.
Repairs photodamage
HPR Hydroxypinacolone Retinoate Inhibits UV-induced enhancement of MMP activity, protecting elastic fibers
Repairs acne
Reduces hyperkeratosis in the sebaceous glands, promotes keratin metabolism, and unclogs pores
Treats acne and oil
Reduces oil secretion, reduces acne breakouts, and reduces pigmentation left over from acne
Improves the skin barrier
Promotes keratinocyte activity, increases epidermal thickness, strengthens the epidermis, and reduces skin damage.
Cosmetic Applications of HPR Hydroxypinacolone Retinoate
1. Anti-aging, firming, and improving skin texture
2. Lightening and brightening, reducing melanin
3. Acne treatment, improving acne
4. Antioxidant, reducing skin roughness
5. Oil control and inhibiting sebum secretion
Summary
Retinoids are a large family of substances with diverse benefits, including anti-aging and sebum suppression. Retinoids are similar in structure and function to retinol, but differ in potency and irritation due to differences in side chain structure. Retinoids like retinoic acid (tretinoin) are highly irritating and potent, making them suitable for pharmaceutical applications. Retinol and its esters can be converted into each other, ultimately exerting their effects, making them gentler, but with some impact on their potency.
HPR Hydroxypinacolone Retinoate. is a revolutionary new retinoid. Research has shown that, compared to other vitamin A products, it can directly activate receptors without requiring metabolic conversion (typically, retinol requires a two-step conversion process within the skin). This results in less irritation, yet high potency, greater stability, and reduced oxidative degradation. It is a safe and effective anti-aging (effectively reducing fine lines and wrinkles and fading dark spots) and anti-acne ingredient.
FAQ
Q: What certifications do you hold?
A: We prioritize product quality and safety, and our production facilities hold several top international certifications, including:
· cGMP
· ISO9001 and ISO22000
· BRC
· HACCP
· EU and NOP organic certifications
· Kosher certification
· Halal certification
Q: Do you provide third-party test reports (COAs) for your products?
A: Of course. We provide a COA with every batch.
Q: Do you offer custom products and technical support?
A: Yes, we have a strong R&D team. In addition to standard products, we can also provide customized dosage forms and customized packaging to meet your specific needs.
Our technical team is always ready to provide comprehensive technical support, including product application and formulation advice.
Q: What other related products do you have?
A: Yes, in addition to HPR Hydroxypinacolone Retinoate, we have a wide range of cosmetic raw materials, including:
Whitening ingredients: Niacinamide, Vitamin C and its derivatives, Arbutin, Tranexamic acid, Kojic acid and its derivatives, Plant extracts (such as Glabridin, Olive Fruit Extract, Centella Asiatica Extract, etc.)
Anti-aging ingredients: Retinol, Peptides (such as Oligopeptide-1, Oligopeptide-68), Bosin, Astaxanthin, GABA, Ectoin, etc.
