95% Asiaticoside Centella Asiatica Extract CAS 16830-15-2
Centella Asiatica: A Skin Repair Expert
Asiaticoside is a major active ingredient extracted from the plant Centella asiatica (L.) Urban, belonging to the triterpenoid saponin class of compounds. It is commonly found in its leaves and is often referred to as "plant collagen." In traditional Chinese medicine, this ingredient is believed to have the effects of "clearing heat and detoxifying, reducing swelling and promoting tissue regeneration," and is often used to promote wound healing and relieve inflammation. Further research reveals that asiatica has multiple biological activities, including inhibiting scar formation, promoting wound healing, neuroprotection, anti-anxiety effects, and immunomodulation. Its wide application in skin repair and beauty, effectively improving skin damage and reducing scar formation, has thus attracted the attention and application of many skincare and pharmaceutical brands.
YTBIO: Providing High-Quality Asiaticoside and Services
Asiaticoside: Mechanism of Action and Effects
1. Moisturizing and Nourishing
Asiaticoside contains multiple moisturizing factors that enhance the skin barrier's ability to retain moisture, continuously improving dry and rough skin, leaving it lastingly hydrated.
2. Firming and Anti-wrinkle
This ingredient promotes skin cell proliferation and metabolism, accelerates the synthesis of collagen and elastin, thereby improving skin elasticity, reducing wrinkles and fine lines, and delaying the skin aging process. Studies show that within the addition range of 0.25%–4%, asiaticoside can effectively upregulate the expression of collagen and elastin-related genes, making it suitable for anti-wrinkle and firming skincare products.
3. Skin Repair
Asiaticoside effectively accelerates wound healing and inhibits scar hyperplasia by promoting collagen synthesis, angiogenesis, and granulation tissue growth. This mechanism is not only supported by traditional experience (such as tigers using asiaticoside to treat wounds) but also applicable to modern clinical treatments of trauma, burns, and postoperative scars. Simultaneously, it strengthens fibroblast activity, enhances epidermal barrier function and stratum corneum integrity, and strengthens the skin's self-defense capabilities.
4. Anti-inflammatory and Soothing
Centella Asiatica extract (CAE) can target and inhibit the release of pro-inflammatory cytokines (such as TNF-α, IL-6, IL-1β) and growth factors (such as TGF-β, PDGF, VEGF), thereby relieving inflammatory reactions such as redness and stinging, making it particularly suitable for sensitive and unstable skin.
5. Antioxidant and Firming
Asiaticoside works synergistically with hyaluronic acid and peptides to enhance antioxidant defense capabilities, reduce damage to fibroblasts from reactive oxygen species (ROS), and promote type I collagen synthesis through multi-target regulation, thereby synergistically improving skin firmness and elasticity.
Core Mechanism of Action
Promotes wound healing: Activates epithelial cells, promotes granulation tissue formation, and accelerates wound repair.
Inhibits scar formation: Regulates the balance between collagen synthesis and degradation, reduces abnormal scar hyperplasia, and improves scar texture.
Asiaticoside: Multiple Applications
Cosmetics
Repair and Soothe: Promotes skin barrier repair, relieves redness and stinging in sensitive, acne-prone, and sun-damaged skin; commonly used in repair serums and masks.
Anti-wrinkle and Firming: Improves skin elasticity by promoting collagen synthesis, reducing wrinkles; often combined with hyaluronic acid and peptides.
Moisturizing and Nourishing: Enhances the stratum corneum's water-retention capacity, improves dryness and roughness, and maintains skin hydration.
Acne Treatment and Conditioning: Regulates sebum secretion, repairs acne-prone skin, and reduces acne scars.
Medical Field
Wound Repair: Promotes the healing of surgical incisions, burns, and other external injuries, and inhibits scar formation.
Scar Management: Improves keloids and hypertrophic scars, regulates collagen metabolism, and improves scar texture.
Chronic Ulcer Treatment: Adjunctive treatment for difficult-to-heal wounds such as diabetic foot ulcers and varicose ulcers.
Skin disease treatment: Used to treat skin problems such as acne and scleroderma, regulating inflammatory responses and improving skin condition.
Health supplements
Some health supplements contain asiaticoside, a natural ingredient with antioxidant and immunomodulatory effects; however, its specific effects vary from person to person.
