4-Hexyl-1,3-benzenediol/4-Hexylresorcinol CAS 136-77-6
What is 4-Hexylresorcinol?
4-Hexylresorcinol, with a molecular formula of C₁₂H₁₂O₂ and a molecular weight of 197.24, appears as a white powder and is commonly used as an antioxidant, pigment stabilizer, color protectant, and whitening agent. Hexylresorcinol has a long history of application, not only as a pharmaceutical active ingredient but also for preventing browning in fruits, vegetables, and shrimp. As a safer raw material, 4-HR was initially used to prevent browning in shrimp, acting as an effective inhibitor of tyrosinase in shrimp. It has subsequently been used in cosmetics as a whitening ingredient, boasting diverse applications such as whitening, antibacterial, and anti-aging. With continued research and development, more related products are expected to be developed in the future.

YTBIO: Providing High-Quality 4-hexylresorcinol and Services
High-quality nutritional supplements are crucial to your health journey. YTBIO specializes in providing high-quality 4-hexylresorcinol.
Why choose YTBIO? We hold the following certifications:
- cGMP, ISO9001, and ISO22000 certifications ensure rigorous quality control throughout the entire process;
- BRC and HACCP system certifications ensure product safety and reliability;
- EU and NOP organic, kosher, and halal certifications meet various global standards and dietary requirements.
We specialize in the research, development, and production of natural plant extracts, cosmetic active ingredients, and health foods. We primarily produce plant extracts, health food ingredients, and a variety of end-use products, including capsules, softgels, granular capsules, gummies, tablets, and solid beverages. Our production facilities and equipment meet national standards, and our production processes strictly adhere to GMP requirements. If you have any questions, please feel free to contact us at sales@sxytorganic.com
Effects of 4-Hexylresorcinol
Whitening and Spot Removal
By inhibiting tyrosinase activity, it blocks melanin production, reduces dark spots and dullness, and improves uneven skin tone. Clinical studies have shown that a 0.4% concentration of 4-Hexylresorcinol in serum for eight weeks significantly reduced skin melanin content (decrease in MI) and improved skin brightness (increase in ITA°), achieving results superior to the control group.
Antioxidant Effects
Scavenges free radicals, reduces oxidative stress-induced skin damage, and delays aging. It inhibits the production of reactive oxygen species (ROS) induced by blue light and ultraviolet light, protecting cells from oxidative damage.
Anti-Inflammatory and Antibacterial Effects
Inhibits inflammatory factors (such as the NF-κB pathway) and reduces skin inflammation. It has antibacterial effects against common microorganisms such as Propionibacterium acnes and Escherichia coli, making it suitable for acne treatment and skin care.
Anti-Glycation
Inhibits glycation reactions, reduces the formation of AGEs (advanced glycation end products), and prevents dullness and sagging caused by glycation.
Autophagy Regulation
Promotes autophagy, aiding in the removal of melanosomes, and assisting in skin whitening and repair.
Applications of 4-Hexylresorcinol
Cosmetic additive
Strong tyrosinase and peroxidase inhibitors, inhibiting melanin production; promotes glutathione synthesis, reducing DNA damage. Used in whitening and anti-aging skincare products, such as serums and creams.
Food additive
Processing of crustaceans such as shrimp and crab (antioxidant, color preservative). 1-Hexylresorcinol is an effective tyrosinase inhibitor in shrimp, inhibiting the formation of black spots and melanosis. Its potent inhibitory effect is highly safe, preventing shrimp heads from darkening and maintaining their optimal color.
Medical additive
Previously used in anthelmintics and oropharyngeal anesthetics, it is now more widely used in cosmetics.

FAQ
Q: What certifications do you hold?
A: We prioritize product quality and safety, and our production facilities hold several top international certifications, including:
· cGMP
· ISO9001 and ISO22000
· BRC
· HACCP
· EU and NOP organic certifications
· Kosher certification
· Halal certification
Q: Do you provide third-party test reports (COAs) for your products?
A: Of course. We provide a COA with every batch.
Q: Do you offer custom products and technical support?
A: Yes, we have a strong R&D team. In addition to standard products, we can also provide customized dosage forms and customized packaging to meet your specific needs.
Our technical team is always ready to provide comprehensive technical support, including product application and formulation advice.










